UNAIDS and the Gates Foundation convened a meeting on 5-6 June, 2025 to consider mathematical modelling evidence on the anticipated epidemiologic impact and cost-efficiency of long-acting injectable lenacapavir (LEN) for HIV prevention in low- and middle-income countries.

The UNAIDS/ World Health Organization (WHO) meeting, Shaping oral PrEP modelling for high-burden countries in sub-Saharan Africa, was held in Geneva in June 2018. Meeting participants represented a broad range of oral pre-exposure prophylaxis (PrEP) stakeholders. They considered the model outputs required to advance PrEP programmes, the data and assumptions used in models, and decision-making around “reasonable use” of resources for PrEP. The principles covered in these discussions can apply to other biomedical HIV prevention tools.

Meeting report — High-level side-event at the 73rd General Assembly of the United Nations, New York, 24 September 2018

Over the course of the three days of the meeting, a shared understanding was achieved that strong measures and targets for HIV service coverage and the impact target for ending AIDS as a public health threat are already in place. There was agreement that a new summary metric that signals countries’ progress towards ending AIDS as a public health threat and ultimately zero new HIV infections, zero discrimination and zero AIDS-related deaths would be a useful addition to (a) dispel the notion that AIDS is no longer a problem or that a tipping point of certain success will soon be reached, and (b) to help drive policy-makers and galvanize continued political commitment and financial investment in the HIV response.

The meeting—titled Cities Ending the AIDS Epidemic—was the first in a week-long series of side events and panels in support of the UN General Assembly High-Level Meeting on Ending AIDS. The High-Level Meeting culminated in an agreement on a 2016 Political Declaration on HIV and AIDS, which provides specific, time-bound targets and actions to get the world on the Fast-Track to ending the AIDS epidemic. The targets and commitments of the 2016 Political Declaration will guide the world in addressing the critical linkages between health, development, social justice, inequality, poverty and conflict. This document summarizes the proceedings of the meeting on 6 June and related events on 7 June.

Information and communication technology (ICT) represents an important new resource for enhancing the reach and effectiveness of HIV programming. Gay men and other men who have sex with men already use ICT to facilitate many kinds of interactions, and a host of private for-profit platforms exist to help men negotiate offline social and sexual encounters.