On 25 October 2005, UNICEF, UNAIDS and other partners launched the 2005-2010 global campaign on children and AIDS: "Unite for children. United against AIDS." The campaign was simultaneously launched in countries around the world.

Children directly affected by HIV and AIDS participated in the global launch held at the United Nations in New York, as did UN Secretary-General Kofi Annan, UNAIDS Executive Director Dr Peter Piot, UNICEF Executive Director Ann M. Veneman, UNICEF Goodwill Ambassador Roger Moore, First Lady of Rwanda Jeannette Kagame and others.

10 October 2005: UNAIDS Executive Director Dr Peter Piot together with UNAIDS staff welcomed the Secretary-General of the United Nations, Kofi Annan, at the UNAIDS Secretariat in Geneva. The Secretary-General met with senior staff and UN HIV-Positive Staff group and addressed UNAIDS secretariat staff.

The President of Portugal Jorge Sampaio presents UNAIDS Executive Director Dr Peter Piot with medal and honourary title “Grande official da Ordem do Infante Dom Henrique” in Lisbon, 3 October.

In New York from 12-16 September, UNAIDS Executive Director Dr Peter Piot participated in the 2005 World Summit, as well as in advance events.

On 16 September, Dr Piot spoke at the launch of the "Treat every child as your own" campaign by the Organization of African First Ladies against HIV/AIDS (OAFLA), where an agreement to strengthen collaboration on the campaign's implementation was signed by UNAIDS, UNICEF and the OAFLA.

On 15 September, at a briefing on women, AIDS and girls' education for First Spouses attending the 2005 World Summit, Dr Piot launched "Educate girls, fight AIDS", a new issues brief from the UNAIDS-led Global Coalition on Women and AIDS.

On 13 September, Dr Piot addressed leaders of the Association of Southeast Asian Nations. He also spoke at an informal breakfast, hosted by UNDP, entitled "Responding to the Challenges of the Millennium Declaration and the AIDS Epidemic: UNAIDS and UN Reform".

On 12 September, Dr Piot spoke at an informal lunch organized by UNAIDS together with UNDP and the International Parliamentary Union (IPU). Entitled "National Policy and the AIDS Response – the Role of Parliamentarians", the event focused on exploring how parliamentarians can become more fully engaged in the response to AIDS.

The "Treat every child as your own" campaign was launched by the Organization of African First Ladies against HIV/AIDS on 15 September, during the 2005 World Summit.

The campaign aims to prevent new infections among young people, and particularly to protect children affected by the disease from stigma.

At the event, UNAIDS Executive Director Dr Peter Piot and Ann M. Veneman, Executive Director of UNICEF, together with Mrs Jeannette Kagame, First Lady of the Republic of Rwanda and President of the Organization of African First Ladies against HIV/AIDS, signed an agreement to strengthen collaboration and to provide technical guidance and assistance with resource mobilization as well as monitoring and evaluation of the campaign's impact.

At an informal briefing on women and AIDS and girls' education for spouses of heads of state attending the 2005 World Summit, the Executive Director of UNAIDS launched "Educate girls, fight AIDS", a new issues brief produced by the UNAIDS-led Global Coalition on Women and AIDS.

In Brazil from 25-28 July, UNAIDS Executive Director Dr Peter Piot attended the 3rd IAS Conference on HIV Pathogenesis and Treatment, held in Rio de Janeiro, where he was invited to deliver the Special Lecture at the conference closing on 27 July. Dr Piot also met with Brazilian government officials, including the newly appointed Minister of Health Saraiva Felipe, and visited community-based projects.

UNAIDS Executive Director Dr Peter Piot briefs the United Nations Security Council, New York, 18 July 2005.

Dr Peter Piot, Executive Director of UNAIDS, addresses the opening of the 7th International Congress on AIDS in Asia and the Pacific (ICAAP), where UNAIDS launched a new report: 'A Scaled Up Response to AIDS in Asia and Pacific'.

In Beijing from 12-16 June, UNAIDS Executive Director Dr Peter Piot met with Premier Web Jiabao and other Chinese leaders. He also addressed students and faculty at the Health Science Center of Beijing University and at China's Central Party School.