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The Agenda for Accelerated Country Action for Women, Girls, Gender Equality and HIV 2010–2014 (Operational Plan) supports the implementation of the UNAIDS Action Framework: Addressing Women, Girls, Gender Equality and HIV.1 The Action Framework was developed in response to the pressing need to address the persistent gender inequalities and human rights violations that put women and girls at a greater risk of HIV, and increase their vulnerability. These factors also threaten the gains that have been made in preventing HIV transmission and in increasing access to antiretroviral therapy. The UNAIDS Action Framework focuses on action in three areas, outlined below, in which UNAIDS2 and UNIFEM can make specific and unique contributions.