Documents

Introducing long-acting injectable lenacapavir as HIV pre-exposure prophylaxis: implementation considerations

11 November 2026

This guide provides practical guidance for countries considering whether and how to introduce LEN for PrEP as part of their HIV prevention response. It supports context-based decision-making on whether and how to introduce LEN, recognizing that decisions should reflect epidemiological need, health system readiness, PrEP programme maturity, financing, supply, and community priorities.