This 2030 Prevention access framework focuses on one of those top-line targets, which covers primary prevention and requires that 90% of people in need of HIV prevention are using effective prevention options by 2030. This target is disaggregated into 15 second-line prevention targets for specific populations and programmes.

The 2030 Prevention Access Framework presents in greater detail the milestones and actions for achieving these targets––all of which are grounded in the three priorities of the Global AIDS Strategy: country-led, resilient and sustainable HIV responses; people-focused services, and community leadership.

Overall, the 2030 HIV prevention access push seeks to accelerate the use of innovations, expand use of the most cost-effective interventions, and confront the sustainability challenges facing the HIV response.

The Gender Assessment Tool for National HIV Responses (Gender Assessment Tool) is intended to assist countries in assessing their HIV epidemic, context and response through an intersectional gender lens, with the aim of strengthening gender-transformative, equitable and rights-based HIV responses. The 2025 tool places greater emphasis on cost-effectiveness, alignment with national plans, integration and sustainability. Together with a new costing tool and monitoring and evaluation plan template, it is designed to inform the development of country investment cases, funding requests to the Global Fund to Fight AIDS, Tuberculosis and Malaria, and other key national opportunities.

This report developed by UNAIDS and the United for Global Mental Health reviews and maps Global Fund investments in priority HIV and TB comorbidities in Grant Cycle 7 (GC7), including key non-communicable diseases (NCDs), cervical,  anorectal and other cancers, and mental health and substance use conditions.  It highlights how countries prioritize and are integrating health services and other interventions with HIV and TB programmes to advance person-centered approaches and to sustain HIV and TB responses. Analyzing approved grants from 103 countries, the report finds strong demand for integrated approaches, with 97% of countries prioritizing at least one comorbidity.  However, it also reveals major funding gaps, limited allocation compared to identified needs, and weaknesses in monitoring and accountability for integrated approaches, services and systems. The report concludes with practical recommendations to protect and scale evidence-informed and rights-based integrated systems, services and other interventions for addressing comorbidities, strengthen performance and outcome measurement, embed community engagement in decision-making, budgeting, performance monitoring and direct integrated service delivery, and reposition technical assistance, offering clear guidance for shaping sustained partnership, strategic investment, and collective commitment to strengthen systems for health and enhance integrated service delivery for more sustainable HIV and TB responses, and ensuring the health and well-being of people living with and at risk of HIV or TB.

This brief introduction to HIV phylogenetics is the first of three briefs on the phylogenetics of HIV. This brief introduces phylogenetics, explains how the genetic code can be read, and shows how the sequences can reveal insights into HIV biology and epidemiology. The second brief explores what we have learned from HIV phylogenetic studies and how HIV phylogenetics can and should be used to support public health programmes. The third brief discusses the ethical considerations of HIV phylogenetics, including the need for appropriate care and safeguards of sensitive information.

References and full report details as well as partner-specific recommendations are available in the main report.