UNAIDS and the Akbaraly Foundation have signed a landmark partnership agreement to reshape how HIV and women’s health are addressed across Madagascar and the Indian Ocean region.

Over the past 15 years, new HIV infections in Madagascar have surged by 151%, and AIDS-related deaths have risen by 279%. Of the estimated 70 000 people living with HIV in the country, only 20% are receiving treatment. These statistics reflect lives and families in jeopardy and communities in need.

This new alliance brings together two organizations with shared goals and complementary strengths. UNAIDS brings decades of global leadership in the HIV response., while the Akbaraly Foundation offers deep community trust and a proven ability to deliver results.

“This agreement goes well beyond organizational cooperation,” said UNAIDS Country Director, Jude Padayachy, “it represents a collective commitment to innovation, equity and results that matter.”

Since its founding in 2008, the Akbaraly Foundation, which also operates in India, Italy and Rwanda, has become a pillar of healthcare delivery in Madagascar, especially in underserved regions. Its mobile unit, LUISA, has travelled more than 25 000 kilometres to provide medical services in remote villages. Over 340 000 women have been screened for cancer and 480 000 people have received life-changing education on cancer prevention.

The partnership will focus on incorporating HIV services into the fixed and mobile Akbaraly medical infrastructure to extend their reach as well as training programmes for health professionals in Comoros to strengthen the region’s response capabilities.

In addition, UNAIDS and the Akbaraly Foundation will coordinate advocacy efforts during global campaigns  such as World AIDS Day and World Cancer Day to strengthen public awareness and reduce stigma. This strategic alliance is a promise to deliver health with dignity, from city centres to the most isolated islands.

UNAIDS has supported eight countries including Mali, Angola, Madagascar, South Sudan, Indonesia, Pakistan, Philippines and Thailand to assess the strengths and weaknesses of their HIV care service delivery systems.

If countries are to succeed in reaching the 95-95-95 HIV targets, their health systems must adopt rights-based, gender-sensitive, and people-centered models to reach the underserved populations and improve service quality.

One such model is the differentiated service delivery (DSD) approach, which is designed to provide HIV services that are adapted to reflect the preferences and needs of people living with and vulnerable to HIV, while reducing unnecessary burdens on the health system.

UNAIDS mobilized Technical Assistance Demand Generation (TADG) funding support from USAID, to bring together national program stakeholders and community groups for a data-driven consensus building process. In each country, participants used a structured health system assessment and strengthening tool, developed by the HIV Coverage, Quality, and Impact Network (CQUIN), of the Columbia University, to make informed decisions on enhancing quality HIV testing, treatment, and care services.

According to participating country teams, the exercise facilitated a breakdown of national program landscapes into clear, actionable focus areas, and improved their understanding of differentiated delivery of HIV care services. Program teams were able to prioritize areas for focus and to streamline decision-making, which will ultimately lead to practical and sustainable enhancement of HIV service provision.

“Considering South Sudan is lagging behind in treatment coverage, this was a very timely technical support exercise, that will strengthen the HIV care response to achieve 95-95-95 targets through collective action, advocacy and investment” said Dr Agai Akec, Director, HIV Programme, Ministry of Health, South Sudan.

The participating countries recognised the value of adopting differentiated service delivery approach to HIV testing, HIV treatment and the management of advanced HIV disease; establishing linkages with related services such as maternal and child health, Tuberculosis and non-communicable disease care, and promoting collaboration between health facilities and the community.

UNAIDS role has been instrumental in using US catalytic resources to mobilize partners including WHO, The Global Fund, and technical support agencies to support national government and community groups to promote a critical area of work for HIV testing and treatment.

"The TADG catalytic funding helped the country beneficiaries to demystify Differentiated Service Delivery and to identify concrete areas for improvement within national programs. I would encourage countries to undertake more of these exercises to make services available and accessible by all, particularly those who have been left behind." said Fodé SIMAGA, UNAIDS Director, Science Systems and Service for All.

For further details and guidance on using the tool, visit:

• CQUIN Capability Maturity Models
• UNAIDS differentiated Service Delivery country profiles
• Technical assistance to accelerate the implementation of WHO recommendations on HIV testing and treatment delivery: insights and lessons learned in 18 countries

Ghana’s efforts to end AIDS has long relied on international support, particularly from the United States. Recent US funding cuts, however, have led to the suspension of critical programmes including human rights, raising concerns for key populations most affected by HIV-related stigma and discrimination.

In this interview, Hector Sucilla Perez, UNAIDS Country Director for Ghana, talks about the current state of the HIV response, the consequences of these funding changes, and the next steps for the country’s HIV response. 

Q: What is the current state of Ghana’s HIV epidemic? 

Ghana has an estimated 330 000 people living with HIV, with two-thirds being women aged 15 and over. In 2023 alone, there were 18 000 new infections and 12 000 AIDS-related deaths. The most affected groups are transgender women, men who have sex with men, female sex workers, and women. While new infections and deaths have decreased over the last decade, the reduction is far below expectations—only a 19% drop in new infections and 35% in deaths since 2010. The country needs to speed up more in the way we are decreasing new infections and deaths. 

Ghana’s HIV response is heavily dependent on international donors. In 2022, Ghana's total expenditure on HIV and AIDS-related activities was approximately US$ 126 million. The Global Fund covers about 29% of this, PEPFAR (the US President’s Emergency Plan for AIDS Relief) about 8.5%, and the UN about 4.5%. PEPFAR support in Ghana has been essential and critical, investing more than US$ 204 million since 2007, mainly in HIV prevention, testing, treatment support, monitoring, and human rights work. 

 Q: What specific activities has PEPFAR been supporting in Ghana? 

PEPFAR works in three regions of Ghana, (Western, Western North, and Ahafo), supporting essential catalytic services related to HIV prevention, including PrEP, as well as diagnosis, testing, treatment, and support services. They have also been supporting monitoring and evaluation to strengthen health information systems and improve data accuracy, which is critical for guiding our response. 

Additionally, PEPFAR has been implementing human rights programmes with special emphasis on eliminating HIV-related stigma and discrimination. While they do not procure antiretroviral treatment in Ghana, they provide key technical assistance to the health sector on supply chain management for drugs and commodities.

 Q: What has been the impact of the recent US funding cuts? 

The initial pause in US government support affected activities in more than 120 healthcare sites across two regions, affecting 10 civil society organizations collaborating on PEPFAR-implemented programmes. 

Some critical PEPFAR-supported actions were thereafter reinstated due to the waiver, particularly those related to the 95-95-95 targets, with a focus on vulnerable populations, especially adolescent girls and young women, and pregnant women. Monitoring, evaluation, data collection, and technical support for supply chain management were also reinstated. 

However, strategic activities related to human rights with emphasis on stigma and discrimination, community-led monitoring, and interventions focusing on key populations have been definitively suspended. This represents a significant challenge for Ghana's HIV response. 

Q: How is Ghana responding to these funding cuts, particularly regarding human rights programmes? 

The government, through the Ghana AIDS Commission, has re-established and reinvigorated the Human Rights Stream Committee supported by UNAIDS and the Global Fund Grant. The Committee is currently to analyzing how the country can take over some of these activities. They are looking at integrating HIV more deeply into actions implemented by other government partners such as the Commission for Human Rights and Administrative Justice (CHRAJ), and increasing collaboration with the Ministry of Gender and Social Protection and the Ministry of Labour. UNAIDS provides technical assistance in support to these efforts. 

We are also supporting CHRAJ to develop a handbook on stigma and discrimination through the lens of HIV, health and rights as a sustainable way of embedding continuous professional development in the work of this Government entity on actions focused to address HIV stigma and discrimination. 

UNAIDS in Ghana is also strengthening community leadership particularly networks of PLHIV and key populations to play an important role in leading harmonized CLM initiatives in Ghana in collaboration with Global Fund implementers. This is by means of technical assistance and hands on support to communities to develop concrete priorities aligned to key data gaps, including stigma and discrimination and linkages to treatment adherence. 

UNAIDS has also engaged with the Global Fund to explore using efficiencies in their grants to cover these activities. The Global Fund has shown willingness to potentially develop a strategy where all stakeholders can contribute to maintaining the most relevant human rights activities in Ghana. 

Q: What new initiatives are being developed to address these gaps? 

The UNAIDS country office is developing an umbrella strategy called the "Ghana for Rights Initiative." We envision this as a national movement aimed at promoting and protecting human rights in Ghana, especially for those most affected by inequality, discrimination, and stigma. 

This initiative goes beyond the regular framework for HIV response, focusing more comprehensively on human rights issues such as gender equality, rights of persons in vulnerable situations, access to healthcare and education, and eradication of HIV-related stigma and discrimination. 

The key components are advocacy, capacity building, and community engagement, with a strong emphasis on community-led monitoring. We are accelerating discussions with country partners, including the government, bilateral donors, communities, and the UN agencies to frame human rights in a different approach and mobilize resources for the country to continue priority work on HIV and human rights intersectional agenda. 

 Q: What are your concerns if human rights programmes remain suspended? 

Without these critical human rights programmes, we risk seeing increased stigma and discrimination against people living with HIV and key populations. This could reverse progress made in encouraging people to get tested and access treatment, ultimately leading to more new infections and AIDS-related deaths. 

The suspension of community-led monitoring also means we lose vital data and feedback from those most affected by HIV, making our response less effective and less targeted to real needs on the ground. This is why we are urgently working to find alternative approaches and funding sources to maintain these essential services. 

 Q: What is your message to the international community? 

Now is not the time to step back from supporting the global HIV response. The progress we have made over the past years—reducing new infections, expanding access to treatment, and fighting stigma—has only been possible because of strong international solidarity and partnership. The recent US funding cuts have significantly impacted Ghana’s HIV programmes , especially those focused on human rights, stigma, and discrimination, which are essential to reaching the most marginalized and people in vulnerable situations . 

We urge donors, development partners, and the global community to continue investing in the global HIV response especially in countries like Ghana, particularly in areas that protect and promote human rights. Without this support, we risk reversing decades of progress and leaving behind those who are most in need. Sustained international commitment is crucial to ensure that Ghana can achieve the UNAIDS 95-95-95 targets by 2030 and, ultimately, end AIDS as a public health threat. 

We also invite all partners to join us in innovative approaches, such as the “Ghana for Rights Initiative,” to build a future where everyone—regardless of gender, status, or identity—can live free from stigma, discrimination, and the burden of HIV. 

Noncedo Khumalo grew up in a country with one of the highest HIV prevalence rates in the world, Eswatini—a country landlocked between South Africa and Mozambique.  The 24-year-old has overcome her fair share of difficult times to make ends meet. The recent US funding cuts have now put her future in question.     

“Young girls go for older men because when you finish high school and you want to pursue university, it becomes so hard for us, (economically) so many take a short cut,” she said. 

This was how many of her friends acquired HIV. They had little awareness of HIV or how to protect themselves, she explained. She said that condom use was low and there were many myths about HIV including that it is a curse, only affecting some families. 

Gender-based violence and sexual assault increase the risk of HIV infection. “In some cases, the abuser is a family member who is a bread winner, so women don’t report it,” said Ms Khumalo. 

Dr Nondumiso Ncube, Executive Director of Eswatini’s National Emergency Response Council on HIV/AIDS, says that while the country has managed to consistently reduce new HIV infections, new HIV infections remain stubbornly high amongst the younger population, particularly adolescent girls and young women who are three to five times more likely to be infected than their male counterparts. As a result, Dr Ncube says young women and girls are at the centre of the country’s new HIV strategy.

Ms Khumalo was determined not to be one of these statistics. Every day she walked almost six kilometres to attend school. She got a diploma in social work and became involved with Young Heroes, a local community organization, supported by the United States President’s Emergency Plan for AIDS Relief (PEPFAR) three years ago.  

Through this initiative, Ms Khumalo provided peer counselling to adolescents and young women about how to prevent HIV and about broader sexual and reproductive health. She visited schools and communities, offering information and support to help young people protect themselves against HIV. 

Around 60% of Eswatini’s HIV response was funded by PEPFAR, however, in January the US cut all funding for HIV and issued a stop-work order for Young Heroes, forcing them to scale back their services. Ms. Khumalo lost her job. 

Now unemployed and unable to reach the vulnerable young people she once served, Ms Khumalo fears for the safety of young women and girls in her community, where transactional sex between older men and young women, often motivated by poverty, and sexual and gender-based violence remain widespread. “I’m scared for the future of young people,” she said. “Without these HIV programmes, who will protect them?” 

Nosipho Sacolo, a young woman living near the capital city of Mbabane expressed her fears.  “After managing to stay free from HIV for so many years, we no longer have the services to protect us.”  

UNAIDS Country Director for Eswatini, Nuha Ceesay says HIV prevention services—many of which are now closed—have been a game changer in Eswatini. 

“Eswatini has made huge progress in preventing new HIV infections, with new infections falling by 73% since 2010,” he said.

The country still has some challenges, according to him. More than 1300 young women and adolescent girls are infected every year. And nearly twice the number of women are living with HIV compared to men.

UNAIDS and partners are concerned that the abrupt halt to PEPFAR supported HIV prevention programmes could reverse the gains that have been made. 

A local network of non-governmental organizations (NGOs) working to ensure access to primary health care for people in Eswatini—including populations at high risk of HIV infection—CANGO, says the PEPFAR pause could have dire consequences for the country's HIV response, including a rise in new infections among young women and girls. "85 000 people were benefiting from the support, (now) all the people who were working in the sector, who were supporting our people living with HIV, are now sitting at home," said CANGO Executive Director, Thembinkosi Dlamini.

With PEPFAR’s support Eswatini had managed to ensure 93% of people living with HIV were on lifesaving antiretroviral treatment. This is one of Principal Secretary of the Ministry of Health, Khanyakwezwe Mabuza’s main concerns. “Treatment is not something you can skip,” he said. “We have to make sure that people continue to get their life-saving treatment.”

Meanwhile, Ms Khumalo is still hoping that the government and partners will not abandon the peer outreach workshops. Her livelihood and countless others depends on it as do the people they are helping to stay free from HIV.

As international funding declines, countries reliant on global support to fight HIV are being forced to adapt, and fast. In Tajikistan, the impact of these changes is already being felt. We spoke with Aziza Hamidova, UNAIDS Country Director in Tajikistan, about the country’s achievements over the years, the immediate impact of US funding cuts, and what is at stake for the most vulnerable communities.

Q: How would you describe the progress Tajikistan has made in its HIV response before the recent US funding cuts? 

Tajikistan has made significant progress in its HIV response over recent years. Since 2020, HIV-related mortality has halved. Programmatic data on vertical transmission rates among women in care, suggests the rates have dropped from 2.6% in 2018 to just 0.8% in 2024, with only one case registered this year. Blood transfusion safety has been flawless for nearly 22 years, thanks to efforts by the Global Fund, UNAIDS, and other partners. Antiretroviral treatment costs have also been dramatically reduced—from US $254 to under US $65 per year—due to partnerships with PEPFAR, the Global Fund, and UNAIDS. Antiretroviral therapy is now available to all people living with HIV in the country. Outreach and awareness programmes, particularly for key populations such as people who inject drugs, men who have sex with men, sex workers, young people, and women living with HIV, have ensured good treatment coverage and testing rates. Pre-exposure prophylaxis (PrEP-medicine to prevent HIV) had also been available and promoted through civil society organizations. Importantly, community-led monitoring had become a critical, institutionalized part of the national HIV programme.

Q: What immediate impacts have the US funding cuts had on Tajikistan’s HIV response? 

While the provision of basic HIV services, including testing and treatment at state healthcare facilities, has not been significantly affected—thanks mainly to Global Fund support—there have been notable reductions in outreach and access to services for key populations. PEPFAR’s investments have been crucial in improving the quality and reach of these services. As a result of the funding cuts, outreach, access to PrEP, testing, and counselling have all diminished. Two highly popular community health centres, known for providing stigma-free services, have closed, and community services for key population groups served by these centres have been completely stopped. Community-led monitoring, a vital mechanism for ensuring programme impact and accountability, has also been discontinued.

Q: What are you hearing from communities directly affected by these closures and service reductions? 

Our partners and beneficiaries are reporting the suspension of awareness work, interruptions in comprehensive support programmes, and worsening mental health. We have observed a decreased adherence to antiretroviral therapy, particularly among clients who previously relied on community-led organizations or health centres. Many individuals who were on PrEP no longer feel safe or supported and have dropped out of the programme.

In addition, skilled professionals who provided these services have faced emotional burnout and job instability, with some leaving the sector altogether. Community-led organizations that lost funding for community-led monitoring are now unable to participate meaningfully in advocacy and policymaking or the implementation of the national HIV programme.

Although PEPFAR funding for community health centres and outreach was temporarily restored at the end of April, we are still seeing reduced rates of testing and client engagement, with a number of clients lost to follow-up.

Q: How have the government and partners responded to the funding cuts, and what is UNAIDS doing to support them?

Tajikistan never planned to remain dependent on external support indefinitely.

In 2024, with UNAIDS support, the country conducted a National AIDS Spending Assessment assessment, revealing that over 60% of the national HIV programme was funded externally, mainly by the Global Fund and the US government. In response, the government, with support from UNAIDS, PEPFAR, and the Global Fund, developed its first HIV Sustainability Roadmap, aiming for national programme sustainability by 2030. The abrupt funding interruption was a shock to all stakeholders, prompting emergency actions by the government. Strategic prioritization is now underway with the support of UNAIDS, and while additional state budget funding has been allocated for 2026, it remains insufficient. Mobilizing further external resources, especially for key populations, is still necessary.

Q: What would happen if US funding is not restored or replaced? 

If US funding is not restored or replaced, Tajikistan would be set to lose about 60% of its HIV programme funding. This would risk the progress that we all worked so hard for, potentially returning the country to a time when access to testing and treatment was limited. Disruptions in prevention, testing, treatment, and care would occur, and gains achieved over years of dedicated work could quickly unravel. The most vulnerable populations would be at greatest risk, and the overall effectiveness of the national HIV response would be severely compromised.

Q: What message do you have for the international community? 

The HIV response in Tajikistan, as in many countries, is a testament to the power of global solidarity and smart investments. Collective action by donors, governments, organizations, communities and civil society has saved millions of lives. Now, when we are so close to the 2030 goal of ending AIDS, this solidarity must not falter. Continued support is essential to preserve progress and prevent a reversal of the gains made.

The Joint United Nations Programme on HIV/AIDS (UNAIDS) leads the global effort to end AIDS as a public health threat by 2030 as part of the Sustainable Development Goals.

Following the US funding cuts in January, UNAIDS is working closely with governments and partners in affected countries to ensure that all people living with or affected by HIV continue to access life-saving services. For the latest updates, please visit unaids.org

The United Nations Secretary-General António Guterres will present his report on HIV to the 79^th United Nations General Assembly at the UN in New York on 5 June 2025.

The report, The urgency of now: AIDS at a crossroads – progress report on the 2025 targets and strategic directions for the future, contains a review of progress towards realizing the targets and commitments set out in the 2021 Political Declaration on HIV/AIDS and an outline of the work that still lies ahead.

It comes at a critical moment in the global HIV response, when urgent action is needed to protect the hard-won gains and accelerate progress towards ending AIDS as a public health threat.

UNAIDS has been supporting countries to gradually reduce their reliance on external assistance.

The current Global AIDS Strategy 2021–2026 has led the HIV response with a bold vision of ending inequalities that continue to fuel the epidemic. The midterm review of the Strategy, published as part of the annual Global AIDS Update in July 2024, highlighted key achievements and remaining challenges to inform the development of the next phase of the response.

Under the current strategy, fewer people acquired HIV in 2023 than at any point since the late 1980s. Over 30 million people were receiving life-saving antiretroviral therapy, reducing AIDS-related deaths to their lowest level since the peak of 2004. Significant gains have been made in sub-Saharan Africa, underscoring the power of existing interventions to end AIDS as a public health threat by 2030. As the United Nations approaches its eightieth anniversary, the results of the HIV response stand as a powerful testament to the impact of multilateral action and must be protected.

Amid recent challenges and the fragility of the HIV response, the world is falling behind in achieving the 2025 HIV targets. Obstacles to accessing treatment, insufficient prevention programming, a failure to adequately support the work of communities, rising inequalities and a lack of political will and financial support threaten the response.

The next Global AIDS Strategy, for the period 2026–2031, led by UNAIDS, is being developed at a time when the response to the HIV epidemic is at a crossroads. The strategy will be among the most important in 40 years of response to the pandemic. Developed in a context of instability for many countries, in particular with regard to HIV-related funding, the strategy will be crucial for accelerating the achievement of the 2030 Agenda for Sustainable Development and setting the foundation for a sustainable response to HIV post-2030.

This report is also available in Arabic, Chinese, French, Russian and Spanish.

The sudden stop-work order from the US government in early 2025 triggered a global funding crisis for HIV, sexual reproductive health (SRH), and youth programmes. This abrupt halt has left countless youth-led and youth-serving organizations struggling to survive, with devastating consequences for young people worldwide. The impact is profound, and the need for immediate action is critical.

A survey conducted by Y+ Global, Youth LEAD, Youth RISE, The PACT, and J+LAC in March 2025 among organizations delivering HIV and SRH youth programmes reveals the stark reality faced by youth-led and youth-serving organizations. Forty-five youth-led and youth-serving organizations from around the globe completed the survey, with 56% of responses coming from Eastern and Southern Africa, the region hosting the largest population of young people living with HIV. Sixty percent of respondents reported disruptions to their core HIV services, severely hindering their ability to provide essential HIV prevention, treatment, care, and support. These disruptions directly impact the health and well-being of young people in all their diversity and undermine ongoing efforts to strengthen youth-led HIV responses.

Beyond HIV services, other crucial youth-focused programmes have also been affected, with SRH, mental health, and life-skills education programmes each experiencing a 12% decrease. Furthermore, activities like youth-led advocacy and engagement in policy and decision-making discussions have also been impacted, leaving youth voices under represented and unheard in the HIV response as well as other development areas.

The survey also warns about the abrupt policy changes occurring as a consequence, including the integration of HIV-specific clinics into general health systems, and the surge of restrictive laws targeting organizations working on gender, diversity, and sexual and reproductive health and rights, using the term “foreign agent” to criminalize their work. These changes are causing the collapse of service delivery models and increased barriers to youth-led organizations, further reducing accessibility for young people.

“The funding cuts are not just numbers on a spreadsheet; they represent real lives, real services, and real hopes lost. Youth-led organizations are the lifeline for so many young people, especially those most at risk,” shared Maximina Jokonya, Executive Director of Y+ Global. “We need urgent action from donors and governments to recommit and reinvest in youth leadership and safeguard the future of the HIV response,” she added.

Despite these setbacks, youth-led organizations are showing incredible resilience by launching crowdfunding campaigns, seeking alternative national and international partnerships, and continuing peer outreach with limited resources. Still, the long-term sustainability of these efforts is threatened by the funding crisis.

Youth and the next Global AIDS Strategy

Amidst this crisis, UNAIDS convened two global youth consultations in the context of the Global AIDS Strategy 2026 - 2031 development process to gather young people’s views and priorities for the future of the HIV response. More than 120 young people from diverse young key and vulnerable population groups participated in this consultative process. The key messages resulting from these consultations are unequivocal: young people demand involvement in decision-making spaces of the HIV response and in the development of alternative funding strategies, such as the sustainability roadmaps. They also demand a leading role in the implementation and monitoring of these decisions, as well as the positioning of human rights, gender equality, mental health, and innovation at the centre of the HIV response.

Call to action

Youth-led organizations are making an urgent call to all donors, partners, and policymakers to act now to save youth-led responses by reinstituting traditional funding support, increasing domestic and emergency funding solutions to maintain the operational stability of youth-led organizations, and supporting youth leadership in the HIV response.

Ethiopia, with a population of 130 million, is Africa’s second most populous country. Despite steady economic growth approaching low-middle income status, the country faces a daunting number of challenges, from economic pressures and development needs to recurring natural disasters such as droughts and floods, as well as conflict and other man-made crises. These factors mean Ethiopia still relies heavily on external aid-particularly for food security and humanitarian assistance. 

On top of these existing burdens, HIV remains a significant public health challenge. The country is home to an estimated 610 000 people living with HIV, with over half a million currently on life-saving antiretroviral treatment-most of which is funded by international donors. Recent cuts in US funding have put Ethiopia’s HIV response at risk, threatening to reverse years of progress and placing additional strain on an already fragile health system.

We sat down with Tina Boonto, UNAIDS Country Director for Ethiopia, to discuss the impact of the funding crisis, the government’s response, the resilience of communities, and what needs to happen next to protect Ethiopia’s HIV response.

Q: What is the current situation, and how has the recent US funding crisis impacted the HIV response?

Ethiopia has made significant progress in its HIV response in recent years and is on track to reach the UNAIDS 95-95-95 targets with 90% of people living with HIV in the country being aware of their HIV status; 94% of those diagnosed with HIV receiving antiretroviral (ARV) therapy; and 96% of people on ARV therapy achieving viral suppression. The US Government through PEPFAR and the Global Fund have been the primary funders for the HIV response, supporting treatment for over 530 000 of the estimated 600 000 people living with HIV in the country. However, the sudden cuts had a devastating impact. Critical services have stopped, people have lost their jobs, and many clinics have closed their doors. People living with HIV now face uncertainty about their access to medication, testing, and prevention services. 

In Bahir Dar, for example, programmes for key population have stopped, outreach workers have lost their jobs, and peer support groups have been terminated. It’s heartbreaking to see the situation on the ground. Clients arrived at clinics to find them closed, and many were left without guidance or support. 

Women are anxious about the availability of medication and prevention tools like condoms. Without these, the risk of HIV transmission increases, and the health of those already living with HIV deteriorates. Some cannot even afford basic necessities like food, let alone treatment. 

Q: How are communities responding to the collapse of HIV services? 

Despite the collapse, communities are showing incredible resilience and a fighting spirit. Peer educators, youth groups and mothers are stepping in where formal systems are failing. For example, in the Afar region, a case manager working with people living with HIV continued his outreach work despite funding cuts. He was able to get funding from the health bureau and shared “even if the money is not enough, I’m happy to continue to help reach people living with HIV, providing pregnant women information on how to prevent transmission to their babies”. 

But while these community-led efforts are inspiring, they cannot replace the need for sustainable funding. Community members often live below adequate income levels, and they need support for basics like transport and food. UNAIDS is encouraging the government to consider a social contract with community organizations-similar to Ethiopia’s successful Health Extension Worker model-so that peer outreach workers can be formally supported and paid for their essential outreach work. 

The reason why we are pushing for outreach workers to be supported is because stigma and discrimination remain significant barriers. Even after 40 years of the HIV epidemic, people living with HIV in Ethiopia still experience stigma, which deters them from seeking care at public facilities. Many fear being discriminated against or not receiving adequate services. This is why the role of community peer outreach is so vital. Without armies of community outreach workers, especially in high-burden areas, it’s impossible to have a successful HIV programme. 

 Q: What lessons can be drawn from this crisis for the future of HIV response in Ethiopia and beyond? 

The crisis has exposed the fragility of systems built around a single funding stream. When the money stopped, so did services, trust, and hope. We must build resilience into the system from the start. Community-led organizations must be recognized as essential, and youth-led innovation must be scaled up. Emergency preparedness and integrated, people-centered solutions are crucial, especially as HIV intersects with conflict, displacement, and gender-based violence. HIV must remain central to humanitarian, development and recovery agendas-not as an afterthought, but as a foundation.

UNAIDS is also supporting by working on producing an investment case to prioritize key components of the HIV programme for government funding. There are ongoing discussions about new partnerships with the private sector and exploring alternative financing mechanisms. There is political will. The Ministry of Health is considering adopting the methodology of the HIV Sustainability Roadmap to develop a broader health sector sustainability strategy. UNAIDS is supporting these efforts by helping to produce a sustainability strategy and mobilizing resources alongside other donors

Q: What steps is the Ethiopian government taking to address the funding crisis?

The government recognizes this as a wake-up call and is actively considering solutions to find resources to cover priority health issues, including HIV, tuberculosis, and malaria. However, the scale of the challenge is enormous-external assistance for Ethiopia’s health, humanitarian and development needs amounts to around US$ 2.7 billion annually. The government is exploring options such as introducing a social tax, where all workers would contribute to health funding, but this is still under parliamentary discussion. While these efforts are encouraging, they are not yet sufficient to fill the gap left by international donors. 

Q: How is UNAIDS supporting the government and the HIV response during this crisis? 

UNAIDS is playing a critical role. In response to the funding crisis, we conducted immediate impact surveys to understand which programmes have stopped or are ongoing, and what the consequences are on the ground. This information feeds into the national plans and sustainability plan.

We are also producing an investment case to help the government prioritize key components of the HIV programme for domestic funding. Our costing data enables us to propose affordable models, like social contracting with community organizations.

We are reviving HIV prevention efforts, including using AI-powered digital platforms and chatbots to reach young people with real-time information. Ethiopia was also piloting long-acting injectable antiretroviral medicine to prevent HIV or ‘PrEP’ before the funding cuts stopped this progress.

Finally, we are working closely with the Ministry of Health, the Global Fund, and community organizations to mobilize resources and advocate for integrated, sustainable solutions. 

Q: What is your message to the international community at this critical juncture?

We need global solidarity now more than ever. We are so close to ending AIDS as a public health threat by 2030. Over half a million people in Ethiopia are on antiretroviral treatment—we cannot let them down. The world has come too far, and too many have sacrificed too much to let progress slip away now. We must do everything possible to keep the lights on for the HIV response, both in Ethiopia and globally.

The resilience of Ethiopian communities is inspiring. People are refusing to give up, finding new ways to support each other and keep the response alive. With renewed commitment from the government, partners, and the international community, we can protect the progress made and continue moving towards ending AIDS as a public health threat.

The Joint United Nations Programme on HIV/AIDS (UNAIDS) leads the global effort to end AIDS as a public health threat by 2030 as part of the Sustainable Development Goals. 

Following the US funding cuts in January, UNAIDS is working closely with governments and partners in affected countries to ensure that all people living with or affected by HIV continue to access life-saving services. For the latest updates, please visit unaids.org

In the heart of Chișinău, Moldova, medical students, healthcare workers, civil society members, and representatives of the international community took a symbolic step toward a more inclusive, respectful, and stigma-free health system.

To commemorate International AIDS Candlelight Memorial Day and under the theme of “In Their Shoes”, the event was organized by UNAIDS in partnership with the Association of Medical Students and Residents, the Nicolae Testemițanu State University of Medicine and Pharmacy and the Ministry of Health of the Republic of Moldova. The event marked a growing movement to end HIV-related stigma in Moldova’s healthcare system—a transformation already underway in medical education.

Since 2023, the Nicolae Testemițanu State University of Medicine and Pharmacy, with technical support from UNAIDS and financial backing from the Embassy of Sweden, has introduced Human Rights in Healthcare as a compulsory course across all faculties. Rather than remaining a stand-alone subject, human rights principles are now embedded in core clinical disciplines such as surgery, gynecology, oncology, infectious diseases, and family medicine, including training on how to treat people living with HIV and members of key populations.

“Patients today are more informed. They understand their rights,” said Dr Virginia Salaru,

vice-director of the Didactic and Academic Quality Management Department and Associate Professor. “And medical professionals must be ready, not just scientifically, but ethically.”

This reform is timely. Despite progress in HIV prevention and treatment, stigma in healthcare remains a major barrier. According to the Stigma Index 2.0, people living with HIV, especially those from key populations such as people who use drugs, sex workers, men who have sex with men, and transgender people, continue to face breaches of confidentiality, avoidance by medical staff, and discriminatory treatment.

“Despite all our achievements today, despite having antiretroviral therapy, knowledge, and experience, I still hear stories of despair, rejection, and stigma every day. Sadly, people are still dying, not from the virus, but from attitudes and indifference,” said activist Irina Goreaceaia.

“As the authority responsible for public health, we want every person living with HIV to have equal access to diagnosis, treatment, and support,” said Angela Paraschiv, Secretary of State, Ministry of Health. “HIV does not have to be a social condemnation. The health system offers the support people need to live normal lives — with dignity, not isolation.”

In partnership with UNAIDS, the university conducted a curriculum review through a human rights lens. It identified critical gaps including the fact that, while ethics were taught in theory, students were not being prepared to navigate real-world complexities such as stigma, patient diversity, and discrimination. The updated curriculum now trains students in assertive communication, confidentiality, and patient autonomy regardless of HIV status, gender identity, or background.

“Healthcare should be a place of healing, not harm,” said Svetlana Plamadeala, UNAIDS Country Director for Moldova. “Stigma has no place in clinics, hospitals, or maternity wards. Every person living with HIV deserves privacy, respect, and access to care.”

This effort is part of the broader United Nations programme which includes training more than 250 healthcare workers in rights-based approaches and stigma reduction. Called “Strengthening Human Rights on Both Banks of the Nistru River,” the programme consists of a series of student-led initiatives, public awareness campaigns, and community engagement to reinforce these lessons across Moldova’s campuses and clinics.

Early results are promising. Anonymous student evaluations show high satisfaction with the human rights curriculum, and practical implementation has already started across disciplines.

“In addition to the Human Rights course, the campaigns, flash mobs, and student-led initiatives really opened our eyes,” said Cătălina Repesciuc, a second-year student at the university. “Understanding stigma, especially around HIV, is essential not just in theory, but for how we interact with real patients in everyday practice.”

Katarina Fried, Ambassador of Sweden to Moldova, emphasized that “this initiative combines solidarity, education, and human rights. Our project with the UN reinforces these values on both sides of the Nistru River. The active involvement of students and health authorities shows what social responsibility looks like in action.”

Moldova’s message is clear: healthcare must be grounded in respect, dignity, and rights. And thanks to support from UNAIDS and Sweden, that transformation is already underway — in the classroom, in clinics, and in the minds of the next generation of healthcare professionals.

“You wear a white coat for only a few hours a day, the rest of the time, you are a patient like anyone else,” said Dr Cocieru-Salaru. “Treat your patients the same way you want to be treated. Always ‘walk in their shoes’,” she added.

The global response to HIV has reached a crucial juncture. Groundbreaking scientific advances, including the development of long-acting HIV prevention technologies like lenacapavir and cabotegravir, offer a transformative opportunity to curb the epidemic.

Long-acting injectables, which were hailed by Science magazine as one of the major breakthroughs in science in 2024, have shown exceptional efficacy, with lenacapavir demonstrating nearly 100% protection against HIV infection.

Despite these unprecedented advancements, the HIV response faces a dire threat from severe funding cuts. With more than 1.3 million new HIV infections annually, three times the target for 2025, financial constraints and a lack of sustained political will threaten to undo decades of progress. Global health experts warn that without urgent action to ensure continued investment, the ability to scale these life-saving technologies will be jeopardized, leaving millions at risk.

On the eve of the 78 World Health Assembly, global health leaders, government ministers, pharmaceutical companies, and civil society representatives gathered at UNAIDS headquarters in Geneva for the High-Level Multisectoral Leadership Dialogue on HIV Prevention. This High-Level dialogue, organized by the Global HIV Prevention Coalition and co-hosted by UNAIDS in collaboration with UNFPA, WHO, and UNDP, the Federal Republic of Brazil, and the Kingdom of the Netherlands, focused on accelerating access to long-acting HIV prevention technologies and advancing sustainable prevention systems.

Referring to the current funding crisis, Winnie Byanyima, Executive Director of UNAIDS, warned that “If we continue down this path, we could see an additional 6 million HIV infections and 4 million AIDS-related deaths by 2029. Put simply, we will lose control of the AIDS pandemic. But we have an opportunity today. We have new, long-acting HIV prevention tools that could fundamentally reshape the HIV response, putting us back on the right path.” 

Global leaders presented successful national models from Africa, Asia and Latin America, illustrating how innovative prevention strategies are being implemented despite financial challenges. Mariangela Simao, representing Brazil, said “PrEP in Brazil is now a reality. We initially set a target of reaching 50,000 people with PrEP by 2025, but we’ve already surpassed that milestone, with 122,000 people currently using it. Our next goal is to reach 300,000 users by next year. Data shows that HIV incidence is declining in cities with more than 100,000 inhabitants where PrEP coverage is higher.”

Global HIV Prevention Coalition co-chair and CEO of AVAC, Mitchell Warren called for choice in HIV prevention.

“Condoms work well for some people and situations. Oral PrEP is safe and effective for those who can adhere to daily pill taking. The monthly dapivirine vaginal ring is a preferred option for some women, as is voluntary medical male circumcision for many men, while harm reduction is highly effective for people who inject drugs. Now, long-acting injectables offer an additional option for the many people who struggle to protect themselves from HIV and want more convenient and discreet prevention options.”

Key panel discussions focused on the cost of inaction, the significance of equity in access, and the role of long-acting prevention in the future HIV prevention toolkit.

The event underscored the urgent need for a multisectoral approach to overcoming structural barriers to prevention, including regulatory, financial, and societal challenges. The discussions highlighted that global solidarity and sustained political will are essential to closing the prevention gap and achieving the UNAIDS 2030 targets of fewer than 200 000 new HIV infections annually.

Ambassador Paul Bekkers, Permanent Representative of the Netherlands to the UN, closed the dialogue with a powerful call to action: “Not acting now means leaving a larger HIV epidemic to the next generation. Or we can put the world on course to achieve HIV epidemic control and eventually the end of AIDS as a threat to public health. As members of the Global HIV Prevention Coalition, we can achieve this together.”

As part of this pivotal moment, UNAIDS and the Global HIV Prevention Coalition launched a new brochure titled An HIV breakthrough in a moment of crisis: How can we seize this historic opportunity?